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frameshift mutation

  • 移码突变:一种基因突变,它插入或删除的核苷酸数量不是三的倍数,改变了突变下游基因部分的读取框架,导致其编码完全不同的蛋白质序列。

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  移码突变

移码突变(frameshift mutation ) :在正常的DNA 分子中,碱基缺失或增加非3的倍数,造成这位置之后的一系列编码发生移位错误的改变,这种现象称移码突变

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  框移突变

frameshift mutation框移突变): a mutation of insertion or deletion of a genetic material that leads to a shift in the translation of the reading fra...

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短语

reading frameshift mutation 读框移码突变

Frameshift mutation frequency 移码突变率

suppressible frameshift mutation 可抑制移码突变

frameshift mutation phaseshift mutation 移码突变

frameshift t mutation 移码突变

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  • 移码突变 - 引用次数:11

    Because cd53 (-T) results in a 59 amino acidsβglobin variant, it is the first frameshift mutation reported in exon 2 leading to a truncatedβ-globin variant and producing dominantly inheritedβthalassemia.

    由于cd53(-T)导致含有59个氨基酸的β珠蛋白变异体,所以这是第一个位于第二外显子上的导致截短的β珠蛋白变异体并引起显性遗传性β地贫的移码突变

    参考来源 - 一种见于苗族家系的导致显性遗传性β地中海贫血的新移码突变的鉴定
  • 移码突变

·2,447,543篇论文数据,部分数据来源于NoteExpress

Frameshift mutation

  • abstract: A frameshift mutation (also called a framing error or a reading frame shift) is a genetic mutation caused by indels (insertions or deletions) of a number of nucleotides in a DNA sequence that is not divisible by three. Due to the triplet nature of gene expression by codons, the insertion or deletion can change the reading frame (the grouping of the codons), resulting in a completely different translation from the original.

以上来源于: WordNet

双语例句

  • Results all samples of water have plenty of direct mutagen and a small amount of indirect mutagen of base frameshift mutation.

    结果水样大量碱基移码型的直接突变少量的需经代谢活化的碱基移码型的直接致突变物。

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  • In Ames assay the strains were TA98 and TA100, which were able to determine base pair substitutions and frameshift mutation respectively.

    所用的菌种TA98TA10 0 ,主要考察碱基对置换突变和移码致突变。

    youdao

  • The mutations in patients with factor V deficiency were identified including point mutation, frameshift mutation, deletion and insertion mutation.

    课题具有先天性出血倾向的门诊患者进行筛查的过程中,发现了一例重型凝血因子V缺乏症患者。

    youdao

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